Description

Prednisolone 21-Glucoside is a synthetic glucocorticoid derivative, specifically a glycosylated form of prednisolone. This chemical modification is significant as it can alter the compound's solubility, bioavailability, and metabolic profile, making it a valuable intermediate in advanced pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for the synthesis of novel corticosteroid-based therapeutics and for probing metabolic pathways.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel corticosteroid drugs and prodrugs.
• Metabolic Studies: Used in research to study the glucuronidation pathways and metabolic fate of steroid compounds.
• Prodrug Development: Investigated for creating targeted drug delivery systems with modified release characteristics.
• Reference Standard: Serves as a high-purity analytical standard in quality control laboratories for method development and validation.
• Biochemical Research: Employed in enzymatic studies and as a substrate for glucosidase enzymes.

Basic Information

Product Name	Prednisolone 21-Glucoside
CAS No.	88158-44-5
Molecular Formula	C27H38O12
Molecular Weight	554.59 g/mol
Synonyms	Prednisolone 21-β-D-Glucopyranoside; 11β,17α,21-Trihydroxypregna-1,4-diene-3,20-dione 21-β-D-glucoside; 21-(β-D-Glucopyranosyloxy)-11β,17α-dihydroxypregna-1,4-diene-3,20-dione; Prednisolone glucoside; Glucoprednisolone
EINECS	Contact for details

Quality Control

Our Prednisolone 21-Glucoside is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for research and development use. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.