Description

Pyridine, 3-Fluoro-2,4-Bis(Trimethylsilyl)- (9Ci) is a highly functionalized, organosilicon-protected pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of both fluorine and silyl groups, which provide unique reactivity and serve as protective handles for the selective construction of complex molecules. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries who require sophisticated intermediates for drug discovery and specialty chemical development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a sophisticated precursor for creating specialized nitrogen-containing ligands used in asymmetric catalysis and transition metal complexes.
• Organic Electronics and Materials: Employed in the research and production of organic semiconductors, liquid crystals, and other functional materials due to its modified electronic structure.
• Cross-Coupling Reactions: The silyl groups can be utilized in Hiyama-type cross-coupling reactions for carbon-carbon bond formation in complex molecule assembly.
• Protecting Group Strategy: Functions as an intermediate where the trimethylsilyl groups act as protective moieties for sensitive pyridine chemistry, allowing for sequential functionalization.

Basic Information

Product Name	Pyridine, 3-Fluoro-2,4-Bis(Trimethylsilyl)- (9Ci)
CAS No.	87674-19-9
Molecular Formula	C11H20FNSi2
Molecular Weight	241.45 g/mol
Synonyms	3-Fluoro-2,4-bis(trimethylsilyl)pyridine; 2,4-Bis(trimethylsilyl)-3-fluoropyridine; 3-Fluoro-2,4-di(trimethylsilyl)pyridine; Pyridine, 3-fluoro-2,4-bis(trimethylsilyl)-; 87674-19-9
EINECS	Contact for details

Quality Control

Every batch of Pyridine, 3-Fluoro-2,4-Bis(Trimethylsilyl)- (9Ci) is produced and analyzed under strict quality management protocols to ensure consistency and purity for research and development applications. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to meet the exacting standards required for synthetic chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.