Description

4-Methyl-2-Trifluoromethyl-Nitrobenzene is a high-purity, multi-functional aromatic intermediate of significant importance in advanced organic synthesis. Its unique structure, featuring both a nitro and a trifluoromethyl group on a methylated benzene ring, makes it a versatile building block for creating complex molecules with tailored properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group often contributes to improved efficacy and environmental profile.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing complex, high-performance dyes and pigments, especially azo dyes.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to construct biaryl systems common in many functional molecules.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research focused on understanding and exploiting the unique effects of fluorine atoms in organic molecules.

Basic Information

Product Name	4-Methyl-2-Trifluoromethyl-Nitrobenzene
CAS No.	87617-21-8
Molecular Formula	C9H6F3NO2
Molecular Weight	217.14 g/mol
Synonyms	2-Nitro-α,α,α-trifluoro-p-xylene; 1-Methyl-4-nitro-2-(trifluoromethyl)benzene; 4-Methyl-2-(trifluoromethyl)-1-nitrobenzene; 2-Trifluoromethyl-4-methylnitrobenzene; α,α,α-Trifluoro-2,4-dimethylnitrobenzene; 4-Methylbenzotrifluoride, 2-nitro derivative; p-Xylene, 2-nitro-α,α,α-trifluoro-
EINECS	Contact for details

Quality Control

Our 4-Methyl-2-Trifluoromethyl-Nitrobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent lot-to-lot performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material is suitable for demanding applications in regulated industries, including pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature and tendency to be easily oxidized, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and stability. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.