Description

Emedastine CAS NO 87233-61-2 is a selective histamine H1-receptor antagonist. This compound is a critical active pharmaceutical ingredient (API) valued for its potent anti-allergic properties. It is primarily required by pharmaceutical manufacturers for the formulation of ophthalmic solutions and other therapeutic products targeting allergic conjunctivitis and related conditions.

Application

• Primary Active Pharmaceutical Ingredient (API) in anti-allergic ophthalmic solutions.
• Key intermediate in advanced pharmaceutical synthesis for H1-antihistamines.
• Research and development of novel topical formulations for allergic skin conditions.
• Reference standard in analytical laboratories for quality control and method validation.
• Pre-clinical and clinical studies investigating histamine receptor pharmacology.
• Manufacturing of finished dosage forms under current Good Manufacturing Practice (cGMP) standards.

Basic Information

Product Name	Emedastine
CAS No.	87233-61-2
Molecular Formula	C17H26N2O3
Molecular Weight	306.41 g/mol
Synonyms	Emedastine Difumarate (common salt form); 1-(2-Ethoxyethyl)-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-1H-benzimidazole; Emedastine Difumarate (USP); E-0659; WAL 801 CL; LG-30435; Difumarate salt of Emedastine
EINECS	Contact for details

Quality Control

Our Emedastine is produced under strict quality management systems. It meets high-purity standards suitable for pharmaceutical applications, with comprehensive testing including identity, assay, and impurity profile analysis. Certificates of Analysis (COA) confirming compliance with relevant specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.