Description

Timobesone is a synthetic corticosteroid compound with significant anti-inflammatory and immunosuppressive properties. Its primary value lies in its potent topical activity, making it a key active pharmaceutical ingredient (API) for targeted therapeutic applications. This compound is essential for manufacturers in the pharmaceutical industry developing advanced dermatological and ophthalmic formulations.

Application

• Topical Corticosteroid Creams and Ointments: Primary API for treating inflammatory skin conditions such as eczema, psoriasis, and dermatitis.
• Ophthalmic Preparations: Used in eye drops and ointments to manage inflammation following ocular surgery or due to conditions like uveitis.
• Veterinary Pharmaceuticals: Incorporated into topical treatments for inflammatory skin disorders in animals.
• Research and Development: Serves as a reference standard and a key intermediate in the synthesis of novel steroid-based therapeutics.
• Compounding Pharmacy: Used by specialized pharmacies to prepare customized medication formulations for specific patient needs.

Basic Information

Product Name	Timobesone
CAS No.	87116-72-1
Molecular Formula	C24H31FO6
Molecular Weight	434.50 g/mol
Synonyms	9α-Fluoro-11β,21-dihydroxy-16α,17α-isopropylidenedioxy-1,4-pregnadiene-3,20-dione; 9α-Fluoro-11β,21-dihydroxy-16α,17α-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione; Timobesone; SQ-27239; Timobeson; SQ 27239
EINECS	Contact for details

Quality Control

Our Timobesone is manufactured under strict quality management systems to ensure it meets the high standards required for pharmaceutical use. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC and related substances tests. A Certificate of Analysis (COA) is provided for every shipment, confirming compliance with established specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.