Description

1-[2-(1-Hydroxyethyl)-5-[2-Hydroxy-3-(Propan-2-Ylamino)Propoxy]Phenoxy ]-3-(Propan-2-Ylamino)Propan-2-Ol Dihydrochloride is a high-purity, non-selective β-adrenergic receptor antagonist (β-blocker) intermediate of significant pharmaceutical importance. This compound matters as a critical building block in the synthesis of advanced active pharmaceutical ingredients (APIs), where its precise chemical structure is essential for biological activity. Pharmaceutical manufacturers and advanced research organizations require this material for developing and producing cardiovascular medications and for pharmacological research applications.

Application

• Pharmaceutical Intermediate: Primary use as a key synthetic precursor in the manufacture of non-selective β-blocker APIs.
• Cardiovascular Drug Synthesis: Essential for the production of medications targeting hypertension, angina pectoris, and arrhythmias.
• Pharmacological Research: Used in biochemical studies to investigate β-adrenergic receptor mechanisms and drug interactions.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical labs.
• Process Development: Employed in R&D for optimizing synthetic routes and scaling up production of related therapeutic agents.
• Custom Synthesis: Basis for the preparation of novel analogs and derivatives for new drug discovery programs.

Basic Information

Product Name	1-[2-(1-Hydroxyethyl)-5-[2-Hydroxy-3-(Propan-2-Ylamino)Propoxy]Phenoxy ]-3-(Propan-2-Ylamino)Propan-2-Ol Dihydrochloride
CAS No.	87049-33-0
Molecular Formula	C22H41Cl2N2O5
Molecular Weight	493.48 g/mol
Synonyms	1-[2-(1-Hydroxyethyl)-5-[2-hydroxy-3-(isopropylamino)propoxy]phenoxy]-3-(isopropylamino)propan-2-ol dihydrochloride; Sotalol Impurity; Sotalol Related Compound; 1,3-Propanediol, 1-[2-(1-hydroxyethyl)-5-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenoxy]-3-[(1-methylethyl)amino]-, dihydrochloride; L-9394; UNII-6A9P3U173Y
EINECS	Contact for details

Quality Control

Our 1-[2-(1-Hydroxyethyl)-5-[2-Hydroxy-3-(Propan-2-Ylamino)Propoxy]Phenoxy ]-3-(Propan-2-Ylamino)Propan-2-Ol Dihydrochloride is manufactured under strict quality management systems. The product undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for pharmaceutical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.