Description

3-Chloro-2,6-Difluorobenzonitrile is a high-purity, multi-functional aromatic nitrile derivative, serving as a critical building block in advanced organic synthesis. Its unique halogenated structure provides a versatile platform for constructing complex molecules, enabling the development of novel compounds with tailored properties. This intermediate is essential for R&D and production teams in the agrochemical and pharmaceutical industries, where precise molecular architecture is paramount for creating active ingredients.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of modern herbicides, fungicides, and insecticides, leveraging its difluoro and chloro substituents for bioactivity.
• Pharmaceutical Building Block: Used in medicinal chemistry for the construction of drug candidates, particularly in molecules targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Liquid Crystal & OLED Material Synthesis: Serves as a starting material for creating specialized fluorinated aromatic compounds used in electronic display technologies.
• Polymer & Resin Modifier: Incorporated to introduce fluorine atoms into polymer chains, enhancing chemical resistance, thermal stability, and surface properties.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki-Miyaura and Buchwald-Hartwig amination to form complex biaryl structures.
• Research & Development: A valuable reagent for academic and industrial research exploring new fluorination methodologies and heterocyclic chemistry.

Basic Information

Product Name	3-Chloro-2,6-Difluorobenzonitrile
CAS No.	86225-73-2
Molecular Formula	C7H2ClF2N
Molecular Weight	173.55 g/mol
Synonyms	2,6-Difluoro-3-chlorobenzonitrile; 3-Chloro-2,6-difluorobenzene carbonitrile; Benzonitrile, 3-chloro-2,6-difluoro-; 86225-73-2; 3-Chloro-2,6-difluorophenyl cyanide
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-2,6-Difluorobenzonitrile adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques including GC, HPLC, and NMR to ensure identity, purity, and consistency. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.