Description

2-Chloro-1-Nitro-4-(Trifluoromethoxy)Benzene is a versatile halogenated nitroaromatic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring chloro, nitro, and trifluoromethoxy substituents, makes it an essential intermediate for creating complex molecules with specific electronic and steric properties. This high-purity intermediate is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for electron-transport materials and charge-generating layers in electronic displays and devices.
• Dye & Pigment Manufacturing: Intermediate for producing high-performance, light-fast azo dyes and complex organic pigments.
• Polymer Modification: Used to introduce functional aromatic groups into polymer chains to alter thermal and optical properties.
• Chemical Research & Development: A valuable reagent for exploring new reaction pathways and creating libraries of compounds for screening in various applications.

Basic Information

Product Name	2-Chloro-1-Nitro-4-(Trifluoromethoxy)Benzene
CAS No.	85578-47-8
Molecular Formula	C7H3ClF3NO3
Molecular Weight	241.55 g/mol
Synonyms	1-Chloro-2-nitro-4-(trifluoromethoxy)benzene; 2-Chloro-1-nitro-4-(trifluoromethoxy)benzene; 4-Trifluoromethoxy-2-chloronitrobenzene; 2-Chloro-4-(trifluoromethoxy)nitrobenzene; 2-Chloro-α,α,α-trifluoro-p-nitroanisole; Benzene, 2-chloro-1-nitro-4-(trifluoromethoxy)-; 2-Chloro-1-nitro-4-trifluoromethoxybenzene; 2-Chloro-4-trifluoromethoxynitrobenzene
EINECS	Contact for details

Quality Control

Our 2-Chloro-1-Nitro-4-(Trifluoromethoxy)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent composition suitable for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for our global B2B partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from heat, sparks, and open flame. Isolate from incompatible materials such as strong reducing agents and strong bases.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.