Description

Tipredane is a synthetic corticosteroid derivative, specifically a potent glucocorticoid receptor agonist. This compound is of significant interest in pharmaceutical research and development for its anti-inflammatory and immunosuppressive properties. It serves as a key intermediate or active pharmaceutical ingredient (API) for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those developing advanced topical and systemic corticosteroid therapies.

Application

• Pharmaceutical Intermediate: Primary use as a critical building block in the synthesis of more complex corticosteroid drugs.
• Anti-inflammatory Drug Research: Serves as a reference standard or active compound in preclinical studies targeting inflammation pathways.
• Dermatological Formulations: Potential use in the development of creams, ointments, or lotions for treating skin conditions like eczema, psoriasis, and dermatitis.
• Immunosuppressive Therapy Development: Investigated for applications in managing autoimmune diseases and preventing organ transplant rejection.
• Analytical Reference Standard: Used in quality control laboratories for method development and assay calibration via HPLC or LC-MS.
• Biochemical Research: Tool compound for studying glucocorticoid receptor (GR) binding, activation, and downstream gene expression effects.

Basic Information

Product Name	Tipredane
CAS No.	85197-77-9
Molecular Formula	C24H31FO6S
Molecular Weight	466.56 g/mol
Synonyms	Tipredane; 9-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 21-(ethylsulfonate); Etiprednol dicloacetate (related ester); SQ-27,519; Glucocorticoid SQ 27,519; 1,4-Pregnadiene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16β-methyl-, 21-(ethylsulfonate)
EINECS	Contact for details

Quality Control

Our Tipredane is produced and tested under a strict quality management system. We provide material that meets high-purity standards suitable for research and pharmaceutical development. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality protocols are designed to ensure consistency and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.