Description

2-Fluoro-4-Methylbenzonitrile is a versatile fluorinated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both an electron-withdrawing nitrile group and a fluorine substituent on a methylated benzene ring, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought by the pharmaceutical and agrochemical industries for research and development, as well as in the production of specialty materials and liquid crystals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a fluorinated aromatic core to modulate bioavailability, metabolic stability, and binding affinity.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in display technologies (LCDs) due to its influence on the mesomorphic properties and stability of the final material.
• Organic Electronic Materials: Employed in the research and development of organic semiconductors, OLEDs, and other electronic materials where its electronic properties are beneficial.
• General Organic Synthesis: Acts as a versatile synthon for further functionalization via reactions of the nitrile group (e.g., hydrolysis to acids, reduction to amines) or via reactions on the aromatic ring.

Basic Information

Item	Details
Product Name	2-Fluoro-4-Methylbenzonitrile
CAS No.	85070-67-3
Molecular Formula	C8H6FN
Molecular Weight	135.14 g/mol
Synonyms	4-Methyl-2-fluorobenzonitrile; 2-Fluoro-p-tolunitrile; 2-Fluoro-4-methylbenzenecarbonitrile; 2-Fluoro-4-tolyl cyanide; 85070-67-3; Benzonitrile, 2-fluoro-4-methyl-; 2-Fluoro-4-methyl-benzonitrile
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Methylbenzonitrile is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and consistent quality suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.