Description

Methyl 2,6-Difluoro-3-Nitrobenzoate is a high-purity, multi-functional aromatic ester building block critical for advanced organic synthesis. Its value lies in the strategic placement of fluorine and nitro substituents, which enable precise molecular modifications and the introduction of key pharmacophores. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, serving as a versatile precursor for active pharmaceutical ingredients (APIs) and complex specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the difluoro-nitrobenzoate moiety contributes to biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic display technologies.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, nucleophilic aromatic substitution (SNAr), and as a scaffold for constructing complex heterocyclic compounds.
• Dye & Pigment Intermediate: Facilitates the production of specialized fluorinated colorants with enhanced properties like lightfastness and chemical resistance.
• Academic & Contract Research: A valuable reagent for methodological development and exploratory chemistry in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	Methyl 2,6-Difluoro-3-Nitrobenzoate
CAS No.	84832-01-9
Molecular Formula	C8H5F2NO4
Molecular Weight	217.13 g/mol
Synonyms	2,6-Difluoro-3-nitrobenzoic acid methyl ester; Methyl 2,6-difluoro-3-nitrobenzoate; Benzoic acid, 2,6-difluoro-3-nitro-, methyl ester; 3-Nitro-2,6-difluorobenzoic acid methyl ester; Methyl 3-nitro-2,6-difluorobenzoate; 84832-01-9; Methyl 2,6-difluoro-3-nitrobenzoate
EINECS	Contact for details

Quality Control

Our Methyl 2,6-Difluoro-3-Nitrobenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency meet the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for each shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; prolonged exposure to light, air, or elevated temperatures should be avoided to maintain product integrity. For long-term storage, consider using an inert atmosphere (e.g., nitrogen or argon).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.