Description

11Beta,21-Dihydroxy-16Alpha-Methylpregna-1,4-Diene-3,20-Dione 11,21-Di(Acetate) is a high-purity steroid derivative and a key pharmaceutical intermediate of significant commercial importance. Its primary value lies in its role as a critical precursor in the synthesis of potent glucocorticoids, enabling the production of advanced anti-inflammatory and immunosuppressive medications. This compound is essential for manufacturers in the pharmaceutical and fine chemical industries engaged in the development and production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of potent corticosteroid drugs, such as dexamethasone and related analogs.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the production of glucocorticoid APIs for treating inflammatory conditions, autoimmune disorders, and allergic reactions.
• Research & Development: Serves as a reference standard and a starting material in medicinal chemistry research for developing new steroidal anti-inflammatory agents.
• Fine Chemical Production: Employed in the manufacture of other specialized steroid derivatives for various therapeutic applications.
• Veterinary Pharmaceutical Manufacturing: Used in the synthesis of corticosteroid treatments for animals.

Basic Information

Product Name	11Beta,21-Dihydroxy-16Alpha-Methylpregna-1,4-Diene-3,20-Dione 11,21-Di(Acetate)
CAS No.	84682-40-6
Molecular Formula	C₂₆H₃₄O₇
Molecular Weight	458.55 g/mol
Synonyms	16α-Methyl-11β,21-dihydroxypregna-1,4-diene-3,20-dione 11,21-diacetate; 11β,21-Dihydroxy-16α-methylpregna-1,4-diene-3,20-dione diacetate; Dexamethasone 11,21-Diacetate; 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione 11,21-diacetate (related); 16α-Methylprednisolone 11,21-Diacetate; 11β,21-Diacetoxy-16α-methylpregna-1,4-diene-3,20-dione; NSC 39471
EINECS	Contact for details

Quality Control

Our 11Beta,21-Dihydroxy-16Alpha-Methylpregna-1,4-Diene-3,20-Dione 11,21-Di(Acetate) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.