Description

Diflorasone 17-Propionate-21-Mesylate is a synthetic corticosteroid derivative, specifically a diester prodrug of diflorasone. This compound is of significant interest in the pharmaceutical industry for its potent anti-inflammatory and immunosuppressive properties. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of advanced topical dermatological treatments.

Application

• Active Pharmaceutical Ingredient (API) Intermediate: A key synthetic precursor in the manufacturing of high-potency topical corticosteroids.
• Pharmaceutical Research & Development: Used in preclinical and clinical studies for novel anti-inflammatory drug formulations.
• Dermatological Preparations: Serves as a critical component in the development of creams, ointments, and lotions for treating psoriasis, eczema, and dermatitis.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Process Chemistry: Utilized in scale-up and optimization studies for the synthesis of final drug substances.

Basic Information

Product Name	Diflorasone 17-Propionate-21-Mesylate
CAS No.	84509-92-2
Molecular Formula	C27H35FO8S
Molecular Weight	538.63 g/mol
Synonyms	Diflorasone 17-propionate 21-methanesulfonate; 6α,9α-Difluoro-11β,17α,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 17-propionate 21-methanesulfonate; 21-Methanesulfonyloxy-6α,9α-difluoro-11β,17α-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione 17-propionate; Diflorasone Dipropionate Mesylate; Diflorasone Propionate Mesylate
EINECS	Contact for details

Quality Control

Our Diflorasone 17-Propionate-21-Mesylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.