Description

1-Bromo-5-Fluoro-2-Methoxy-4-Nitrobenzene is a high-purity, multi-functional halogenated aromatic building block essential for advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging the fluorine and nitro groups for bioactivity.
• Material Science Research: Serves as a precursor for functionalized organic materials, including liquid crystals, dyes, and polymers.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Buchwald-Hartwig amination due to the reactive bromine atom.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags for studying biological systems.
• Academic & Industrial R&D: A versatile reagent for method development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	1-Bromo-5-Fluoro-2-Methoxy-4-Nitrobenzene
CAS No.	84478-77-3
Molecular Formula	C7H5BrFNO3
Molecular Weight	250.02 g/mol
Synonyms	4-Bromo-2-Fluoro-5-Nitroanisole; 2-Bromo-4-Fluoro-5-Nitroanisole; 5-Fluoro-2-Methoxy-4-Nitro-1-Bromobenzene; 1-Bromo-5-fluoro-2-methoxy-4-nitro-benzene; Benzene, 1-bromo-5-fluoro-2-methoxy-4-nitro-; 2-Methoxy-4-nitro-5-fluorobromobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-5-Fluoro-2-Methoxy-4-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.