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2-Deoxy-2-Fluoro-3-o-Methylglucose CAS NO 84243-98-1
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CAS No.:84243-98-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-Deoxy-2-Fluoro-3-o-Methylglucose is a fluorinated glucose analog, a key intermediate in the synthesis of advanced radiopharmaceuticals and diagnostic agents. Its primary value lies in its role as a precursor for positron emission tomography (PET) tracers, enabling non-invasive metabolic imaging. This high-purity compound is essential for research institutions, pharmaceutical developers, and radiochemistry facilities focused on oncology and neurology diagnostics.
Application
- Radiopharmaceutical Precursor: Critical intermediate in the synthesis of PET imaging agents, particularly [18F]FDG analogs and other fluorinated tracers.
- Metabolic Research Probe: Used in biochemical studies to investigate glucose uptake and metabolism in cell cultures and animal models.
- Oncology Diagnostic Development: Serves as a building block for developing novel PET tracers targeting tumor metabolism and proliferation.
- Neurological Disorder Research: Applied in the creation of imaging agents for studying brain glucose metabolism in conditions like Alzheimer's disease and epilepsy.
- Glycoscience & Medicinal Chemistry: A valuable fluorinated synthon for modifying sugar structures in drug discovery and carbohydrate-based therapeutic development.
- Quality Control Reference Standard: Used as an analytical standard in pharmaceutical QC labs to validate the purity of final radiopharmaceutical products.
Basic Information
| Item | Details |
|---|---|
| Product Name | 2-Deoxy-2-Fluoro-3-o-Methylglucose |
| CAS No. | 84243-98-1 |
| Molecular Formula | C7H13FO5 |
| Molecular Weight | 196.17 g/mol |
| Synonyms | 3-O-Methyl-2-deoxy-2-fluoroglucose; 2-Fluoro-2-deoxy-3-O-methyl-D-glucose; 2-Deoxy-2-fluoro-3-O-methyl-D-glucopyranose; 3-O-Methyl-2-fluorodeoxyglucose; FDG-3-OMe; 2-FDG-3-O-Methyl Ether; Precursor for [18F]fluoro-3-O-methyl-D-glucose |
| EINECS | Contact for details |
Quality Control
Our 2-Deoxy-2-Fluoro-3-o-Methylglucose is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and specific tests for residual solvents and impurities. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research and pharmaceutical intermediate standards.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to maintain stability and purity.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 0.5% |
| Residual Solvents (GC) | Meets ICH guidelines |
| Specific Rotation | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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