Description

Esmolol is a highly selective, ultra-short-acting β-1 adrenergic receptor blocker. This compound is critical for its rapid onset and short duration of action, allowing for precise hemodynamic control. It is primarily needed by the pharmaceutical industry for the formulation of injectable solutions used in clinical settings for the acute management of tachycardia and hypertension, particularly during surgical procedures.

Application

• Pharmaceutical Active Ingredient (API): Primary use as the active component in sterile injectable formulations for intravenous administration.
• Cardiac Care: Management of supraventricular tachycardia (SVT), atrial fibrillation, and atrial flutter in perioperative and critical care settings.
• Hypertension Control: Used for the short-term treatment of hypertension, especially during and after surgery.
• Clinical Research: Serves as a reference standard and building block in cardiovascular drug discovery and pharmacological studies.
• Formulation Development: Used in R&D for developing new drug delivery systems that leverage its short half-life.

Basic Information

Product Name	Esmolol
CAS No.	84057-94-3
Molecular Formula	C16H25NO4
Molecular Weight	295.38 g/mol
Synonyms	Esmolol Hydrochloride; ASL-8052; (+-)-Esmolol; Methyl 3-[4-[2-hydroxy-3-(isopropylamino)propoxy]phenyl]propionate; Brevibloc; 4'-[2-Hydroxy-3-(isopropylamino)propoxy]butyrophenone methyl ester; ASL 8052
EINECS	Contact for details

Quality Control

Our Esmolol is manufactured under strict quality systems. It undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. Certificates of Analysis (COA) are provided with each batch, detailing specifications for identity, purity, and impurities. We can support compliance with relevant pharmacopeial standards (e.g., USP, EP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.