Description

Dexamethasone CAS NO 83880-70-0 is a potent synthetic glucocorticoid corticosteroid, widely recognized for its powerful anti-inflammatory and immunosuppressive properties. This high-purity active pharmaceutical ingredient (API) is critical for ensuring the efficacy and safety of a wide range of therapeutic formulations. It is an essential raw material for pharmaceutical manufacturers, research institutions, and compounding pharmacies developing treatments for inflammatory conditions, autoimmune disorders, and certain cancers.

Application

• Pharmaceutical API: Primary use as the active ingredient in injectable, oral, and topical corticosteroid medications.
• Anti-inflammatory Therapeutics: Formulation of drugs for treating severe allergies, dermatological conditions, rheumatoid arthritis, and asthma.
• Immunosuppressive Therapy: Key component in regimens for managing autoimmune diseases and preventing organ transplant rejection.
• Oncological Support: Used to manage side effects like edema and nausea in chemotherapy and to treat certain hematologic cancers.
• Ophthalmic Solutions: Manufacture of eye drops and ointments for treating inflammatory eye conditions.
• Veterinary Medicine: Application in anti-inflammatory and immunosuppressive treatments for animals.
• Biomedical Research: Used as a standard and experimental compound in pharmacological and biochemical studies.

Basic Information

Item	Details
Product Name	Dexamethasone
CAS No.	83880-70-0
Molecular Formula	C22H29FO5
Molecular Weight	392.46 g/mol
Synonyms	9α-Fluoro-16α-methylprednisolone; Decadron; Dexasone; Hexadrol; Maxidex; Millicorten; Oradexon; Dexamethasonum; Dexameth; DXM
EINECS	Contact for details

Quality Control

Our Dexamethasone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets or exceeds pharmacopeial standards (USP/EP/BP) for identity, purity, and potency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting critical parameters such as assay, related substances, residual solvents, and specific optical rotation to guarantee batch-to-batch consistency and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Specific Optical Rotation	+77° to +82° (c=1, in dioxane)
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water (KF Titration)	≤ 8.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.