Description

1-(4-Fluorophenyl)Cyclopentanecarbonitrile is a versatile fluorinated nitrile building block, a key intermediate in modern synthetic organic chemistry. Its molecular structure, featuring both a fluorinated aromatic ring and a nitrile functional group, makes it a critical precursor for the development of advanced pharmaceuticals and agrochemicals. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic areas where fluorinated compounds are advantageous.
• Agrochemical Synthesis: Serves as a key precursor in the development of novel herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity, metabolic stability, and lipophilicity.
• Liquid Crystal & OLED Material Research: Used in the research and development of fluorinated organic electronic materials, where its structure can contribute to the desired electronic properties and molecular alignment.
• Advanced Polymer Chemistry: Acts as a monomer or modifier in the synthesis of specialty polymers and high-performance resins, imparting specific chemical resistance or thermal stability.
• Chemical Research & Development: Employed in academic and industrial labs for methodological studies in cross-coupling reactions, cyano group transformations, and the exploration of new fluorination strategies.
• Custom Synthesis & Contract Manufacturing: A requested intermediate for custom synthesis projects where clients require specific, fluorinated cyclic structures for their proprietary development pipelines.

Basic Information

Product Name	1-(4-Fluorophenyl)Cyclopentanecarbonitrile
CAS No.	83706-50-7
Molecular Formula	C12H12FN
Molecular Weight	189.23 g/mol
Synonyms	4-Fluoro-α-(cyclopentylidene)benzenecetonitrile; (4-Fluorophenyl)cyclopentylideneacetonitrile; Cyclopentanecarbonitrile, 1-(4-fluorophenyl)-; 1-(p-Fluorophenyl)cyclopentanecarbonitrile; 4-Fluorobenzylidenecyclopentane carbonitrile; p-Fluorophenyl cyclopentylidene acetonitrile; α-Cyclopentylidene-4-fluorophenylacetonitrile
EINECS	Contact for details

Quality Control

Our 1-(4-Fluorophenyl)Cyclopentanecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for GMP or research-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.