Description

Amebucort CAS NO 83625-35-8 is a synthetic corticosteroid compound of significant interest in advanced pharmaceutical research and development. This compound serves as a key intermediate or active pharmaceutical ingredient (API) for the formulation of potent anti-inflammatory and immunosuppressive medications. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the development of novel therapeutic agents targeting inflammatory diseases, autoimmune disorders, and dermatological conditions. Our supply ensures high purity and batch-to-batch consistency, which are critical for successful R&D and regulatory compliance.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of advanced corticosteroid-based active pharmaceutical ingredients (APIs).
• Anti-inflammatory Drug Development: Used in research and formulation of medications for treating conditions like arthritis, asthma, and inflammatory bowel disease.
• Immunosuppressive Therapy: Investigated for use in formulations aimed at managing autoimmune disorders and preventing organ transplant rejection.
• Dermatological Preparations: A potential key component in the development of topical creams and ointments for severe skin conditions such as eczema and psoriasis.
• Veterinary Medicine: Applied in the development of anti-inflammatory treatments for companion and livestock animals.
• Biochemical Research: Utilized as a reference standard or probe in studies investigating glucocorticoid receptor activity and signaling pathways.

Basic Information

Item	Details
Product Name	Amebucort
CAS No.	83625-35-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Amebucort; 9α-Fluoro-11β,17α,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione; 9α-Fluoro-16α-methylprednisolone; 9α-Fluoro-16α-methyl-1,4-pregnadiene-11β,17α,21-triol-3,20-dione; (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
EINECS	Contact for details

Quality Control

Our Amebucort is manufactured under strict quality management systems to ensure it meets the exacting standards required for pharmaceutical applications. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and GC. A Certificate of Analysis (COA) documenting all test results is provided with every shipment to guarantee traceability and compliance with your internal quality protocols and relevant regulatory guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.