Description

Cyclopentaneacetic Acid, 1-Fluoro--α--Oxo- (9Ci) is a specialized fluorinated organic building block of significant interest in advanced synthetic chemistry. Its core value lies in its unique molecular architecture, which incorporates both a reactive α-oxo acid moiety and a strategically placed fluorine atom on the cyclopentane ring, enabling precise molecular modifications. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and complex intermediates. Its application extends to materials science for creating specialty polymers and fine chemicals requiring specific fluorinated motifs.

Application

• Pharmaceutical Intermediate: A key synthon for constructing fluorinated analogs of bioactive molecules, potentially enhancing metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of new herbicides, pesticides, and fungicides where the fluorine atom can improve efficacy and environmental profile.
• Organic Synthesis Building Block: Serves as a versatile precursor for synthesizing complex natural product analogs and other fluorinated heterocycles.
• Material Science Precursor: Employed in the research of advanced polymeric materials, liquid crystals, and specialty coatings that benefit from fluorinated components.
• Chemical Biology Probe: Useful for labeling studies or as a substrate analog in enzymatic and metabolic pathway investigations.

Basic Information

Product Name	Cyclopentaneacetic Acid, 1-Fluoro--α--Oxo- (9Ci)
CAS No.	83611-30-7
Molecular Formula	C7H9FO3
Molecular Weight	160.14 g/mol
Synonyms	1-Fluoro-α-oxocyclopentaneacetic Acid; 1-Fluorocyclopentan-1-yl)oxoacetic Acid; 2-(1-Fluorocyclopentyl)-2-oxoacetic Acid; α-Oxo-1-fluorocyclopentaneacetic Acid; NSC 406916; 1-Fluoro-1-carboxycarbonylcyclopentane; (1-Fluorocyclopentyl)glyoxylic Acid
EINECS	Contact for details

Quality Control

Our Cyclopentaneacetic Acid, 1-Fluoro--α--Oxo- (9Ci) is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications. We adhere to cGMP principles where applicable to support our customers' development and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is sensitive to fluoride/strong alkali conditions; ensure storage areas are segregated from such materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.