Description

Oxirane, (Fluoromethyl)-, (2R)- is a high-value, chiral fluorinated epoxide building block. This compound is essential for introducing fluorine atoms and chiral centers into target molecules, significantly altering their physicochemical and biological properties. It is a critical intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries, enabling the synthesis of novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of fluorinated active pharmaceutical ingredients (APIs), including antiviral, anticancer, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in creating advanced, fluorinated pesticides and herbicides with improved efficacy and environmental profiles.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers and fluorinated materials.
• Asymmetric Synthesis: A valuable reagent in stereoselective ring-opening reactions to produce chiral fluorinated alcohols, amines, and other functional groups.
• Life Science Research: Employed in medicinal chemistry and chemical biology for probe and tracer molecule development.
• Fine Chemical Production: Intermediate for synthesizing complex fluorinated fine chemicals and specialty reagents.

Basic Information

Product Name	Oxirane, (Fluoromethyl)-, (2R)-
CAS No.	83398-56-5
Molecular Formula	C3H5FO
Molecular Weight	76.07 g/mol
Synonyms	(R)-(-)-Fluoromethyloxirane; (R)-(-)-1-Fluoro-2,3-epoxypropane; (2R)-(-)-(Fluoromethyl)oxirane; (R)-Glycidyl Fluoride; (R)-1-Fluoro-2,3-epoxypropane; (R)-3-Fluoromethyl-oxirane; (R)-Oxiran-2-ylmethyl fluoride
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our chiral fluorinated intermediates. Production adheres to current Good Manufacturing Practice (cGMP) principles where applicable, ensuring batch-to-batch consistency and high optical purity. Every lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing chiral purity, chemical purity, and impurity profiles, verified by advanced analytical techniques including chiral HPLC, GC, and NMR.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.