Description

2,2-Diphenylpropylamine-Sepharose is a specialized affinity chromatography medium designed for the selective purification of target biomolecules. This product is critical for researchers and process developers requiring high-resolution separation and isolation of specific proteins, antibodies, or enzymes. It is primarily utilized in the biotechnology, pharmaceutical, and life science research sectors for downstream processing and analytical applications.

Application

• Affinity Chromatography: For the purification of antibodies, enzymes, and other proteins that interact with the diphenylpropylamine ligand.
• Biopharmaceutical Downstream Processing: A key tool in the purification train for monoclonal antibodies (mAbs) and recombinant proteins.
• Research & Development: Used in academic and industrial labs for studying protein-ligand interactions and developing new purification protocols.
• Enzyme Immobilization: Serves as a solid support for immobilizing enzymes for biocatalysis and industrial enzymatic processes.
• Sample Preparation: For the selective capture and concentration of target analytes from complex biological mixtures prior to analysis.

Basic Information

Product Name	2,2-Diphenylpropylamine-Sepharose
CAS No.	83381-67-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	2,2-Diphenylpropylamine Sepharose 4B; 1,1-Diphenyl-2-propylamine-Sepharose; DPPA-Sepharose; Sepharose 4B coupled with 2,2-diphenylpropylamine; Affinity gel 2,2-diphenylpropylamine; 2,2-Diphenylpropylamine agarose; (2,2-Diphenylpropyl)amine-Sepharose CL-4B
EINECS	Contact for details

Quality Control

Our 2,2-Diphenylpropylamine-Sepharose is manufactured under a rigorous quality management system. Each batch is tested for critical parameters such as ligand density, binding capacity, and matrix stability to ensure consistent and reliable performance. Certificates of Analysis (COA) documenting these specifications are available upon request to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in the supplied storage solution (typically 20% ethanol) to prevent microbial growth and maintain matrix stability. Do not freeze. For long-term storage, ensure the container is securely sealed to prevent evaporation.

Specification

Item	Specification
Appearance	White to off-white suspension
Matrix	Sepharose 4B
Ligand	2,2-Diphenylpropylamine
Ligand Density	Contact for details
Binding Capacity	Contact for details
Particle Size	45-165 μm
Storage Solution	20% Ethanol
pH Stability	3-10 (long term), 2-12 (short term)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.