Description

1-(Difluoromethoxy)-2-Fluoro-4-Nitro-Benzene is a high-purity fluorinated aromatic intermediate of significant importance in advanced organic synthesis. Its value lies in the unique reactivity imparted by the difluoromethoxy and nitro substituents, enabling precise molecular construction. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex molecules for drug discovery and development, particularly for candidates requiring fluorinated motifs to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms contribute to improved efficacy and environmental profile.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals, leveraging its aromatic and fluorinated structure to modify material properties.
• Organic Synthesis Reagent: Employed in academic and industrial R&D labs for constructing complex aromatic ethers and exploring novel fluorination chemistry pathways.

Basic Information

Product Name	1-(Difluoromethoxy)-2-Fluoro-4-Nitro-Benzene
CAS No.	83189-99-5
Molecular Formula	C7H4F3NO3
Molecular Weight	207.11 g/mol
Synonyms	2-Fluoro-4-nitro-1-(difluoromethoxy)benzene; 1-Difluoromethoxy-2-fluoro-4-nitrobenzene; Benzene, 1-(difluoromethoxy)-2-fluoro-4-nitro-; 2-Fluoro-α,α-difluoro-4-nitroanisole; 4-Nitro-2-fluoro-1-(difluoromethoxy)benzene; 2-Fluoro-4-nitrophenyl difluoromethyl ether
EINECS	Contact for details

Quality Control

Our 1-(Difluoromethoxy)-2-Fluoro-4-Nitro-Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.