Description

(3S,5R,6R,7R,8R,9S,10R,13S,14S,15S,16S,17S)-Octadecahydro-17-(3-Hydroxy-1-Propynyl)-10,13-Dimethyl-5H-Dicyclopropa[6,7:15,16]Cyclopenta[A]Phenanthrene-3,5,17-Triol is a high-purity, complex steroidal derivative of significant interest in advanced pharmaceutical research and synthesis. Its intricate polycyclic structure with multiple chiral centers makes it a valuable key intermediate for developing novel therapeutic agents. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for its potential in creating new molecular entities.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block for the synthesis of novel steroid-based drugs and bioactive molecules.
• Research & Development: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Employed in the development and scale-up of synthetic routes for complex natural product analogs.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Biochemical Research: Investigated for its potential interactions with steroid hormone receptors and related biological pathways.
• Fine Chemical Synthesis: Utilized in the multi-step synthesis of specialized, high-value chemical products.

Basic Information

Item	Details
Product Name	(3S,5R,6R,7R,8R,9S,10R,13S,14S,15S,16S,17S)-Octadecahydro-17-(3-Hydroxy-1-Propynyl)-10,13-Dimethyl-5H-Dicyclopropa[6,7:15,16]Cyclopenta[A]Phenanthrene-3,5,17-Triol
CAS No.	82543-17-7
Molecular Formula	C28H40O4
Molecular Weight	440.62 g/mol
Synonyms	17-(3-Hydroxy-1-propynyl)androstane-3,5,17-triol; Dicyclopropa[6,7:15,16]cyclopenta[a]phenanthrene derivative; Steroidal alkyne-triol; 3,5,17-Trihydroxy-17-(3-hydroxyprop-1-ynyl)-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-octadecahydrocyclopenta[a]phenanthrene; Androstane triol alkyne; [3S-[3α,5α,6α,7α,8α,9α,10β,13β,14β,15α,16α,17β]]-Octadecahydro-17-(3-hydroxy-1-propynyl)-10,13-dimethyl-5H-dicyclopropa[6,7:15,16]cyclopenta[a]phenanthrene-3,5,17-triol
EINECS	Contact for details

Quality Control

Every batch of our (3S,5R,6R,7R,8R,9S,10R,13S,14S,15S,16S,17S)-Octadecahydro-17-(3-Hydroxy-1-Propynyl)-10,13-Dimethyl-5H-Dicyclopropa[6,7:15,16]Cyclopenta[A]Phenanthrene-3,5,17-Triol is manufactured under a strict quality management system. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles to ensure it meets the exacting standards required for pharmaceutical R&D and synthesis. Our quality protocols are designed to support cGMP compliance for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.