Description

Bicyclo[4.2.0]Octa-1,3,5-Trien-7-One, 8,8-Difluoro-5-Hydroxy- is a specialized fluorinated bicyclic ketone derivative, serving as a high-value synthetic intermediate. Its unique fused-ring structure and fluorine substitution make it a critical building block for constructing complex molecules with tailored properties. This compound is primarily sought by research and development teams in the pharmaceutical and advanced materials sectors for applications requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in developing new generation herbicides and fungicides, where the difluoro moiety enhances biological activity and environmental stability.
• Advanced Material Synthesis: Building block for creating specialty polymers and liquid crystals with unique optical or electronic properties.
• Organic Synthesis & Catalysis: Valuable scaffold in academic and industrial research for exploring new cycloaddition reactions and catalytic processes.
• Fluorine Chemistry Studies: Essential reagent for investigating the effects of fluorine atoms on the reactivity and conformation of strained ring systems.

Basic Information

Product Name	Bicyclo[4.2.0]Octa-1,3,5-Trien-7-One, 8,8-Difluoro-5-Hydroxy-
CAS No.	82431-18-3
Molecular Formula	C8H6F2O2
Molecular Weight	172.13 g/mol
Synonyms	8,8-Difluoro-5-hydroxybicyclo[4.2.0]octa-1,3,5-trien-7-one; 5-Hydroxy-8,8-difluorobicyclo[4.2.0]octa-1,3,5-trien-7-one; Difluorinated Bicyclic Ketone; Bicyclo[4.2.0]octa-1,3,5-trien-7-one, 8,8-difluoro-5-hydroxy-; 82431-18-3; 8,8-Difluoro-5-hydroxy-bicyclo[4.2.0]octa-1,3,5-trien-7-one
EINECS	Contact for details

Quality Control

Our Bicyclo[4.2.0]Octa-1,3,5-Trien-7-One, 8,8-Difluoro-5-Hydroxy- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and scale-up processes. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP compliance for pharmaceutical development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong alkalis and incompatible materials. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.