Description

5-Fluoro-2-Nitro Benzylbromide is a versatile and highly reactive benzyl bromide derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of functional groups—fluoro, nitro, and bromo—which enable precise molecular modifications and the construction of complex heterocyclic frameworks. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules, especially those targeting central nervous system (CNS) disorders and anti-cancer therapies.
• Agrochemical Synthesis: Used to construct novel herbicides, fungicides, and insecticides by introducing the benzyl moiety into active structures.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Chemical Biology & Proteomics: Employed as a reagent for protein labeling, bioconjugation, and the development of activity-based probes.
• Dye & Pigment Manufacturing: Intermediate for synthesizing specialized nitro- and fluoro-containing dyes and colorants.
• Academic & R&D Laboratories: Fundamental building block for methodological studies in organic chemistry and novel reaction development.

Basic Information

Product Name	5-Fluoro-2-Nitro Benzylbromide
CAS No.	82420-35-7
Molecular Formula	C7H5BrFNO2
Molecular Weight	234.02 g/mol
Synonyms	1-(Bromomethyl)-5-fluoro-2-nitrobenzene; (5-Fluoro-2-nitrophenyl)methyl bromide; 2-Nitro-5-fluorobenzyl bromide; α-Bromo-5-fluoro-2-nitrotoluene; 5-Fluoro-2-nitrobenzyl bromide; 5-Fluoro-2-nitro-α-bromotoluene; Benzene, 1-(bromomethyl)-5-fluoro-2-nitro-; 82420-35-7
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Nitro Benzylbromide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supported by a detailed Certificate of Analysis (COA). We are committed to meeting the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.