Description

2-Fluoro-4-Hydroxybenzonitrile is a versatile fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a cyano group and a hydroxyl group on a fluorinated benzene ring, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Serves as a precursor in the development of modern pesticides and herbicides, where the fluorine atom can enhance biological activity and environmental stability.
• Liquid Crystal Materials: Used in the research and production of fluorinated liquid crystals for advanced display technologies.
• Polymer Chemistry: Acts as a monomer or modifier in the synthesis of specialty polymers, such as polyimides or polyesters, to impart specific thermal or chemical resistance.
• Organic Electronic Materials: Investigated as a component in the development of organic semiconductors and electron-transport materials for OLEDs and other devices.
• Chemical Research & Development: A valuable reagent for method development and exploring new fluorination and cyanation reactions in academic and industrial R&D settings.

Basic Information

Product Name	2-Fluoro-4-Hydroxybenzonitrile
CAS No.	82380-18-5
Molecular Formula	C7H4FNO
Molecular Weight	137.11 g/mol
Synonyms	4-Cyano-3-fluorophenol; 3-Fluoro-4-hydroxybenzonitrile; 2-Fluoro-4-cyanophenol; 4-Hydroxy-2-fluorobenzonitrile; Benzonitrile, 2-fluoro-4-hydroxy-; 2-Fluoro-4-hydroxybenzenecarbonitrile
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Hydroxybenzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) with batch-specific data is provided with each shipment to guarantee traceability and consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.