Description

(7S)-7β-(3-Amino-2,3,6-Trideoxy-α-L-Lyxo-Hexopyranosyloxy)-9α-Methyl-7,8,9,10-Tetrahydro-6,9,11-Trihydroxynaphthacene-5,12-Dione is a complex, high-purity naphthacenequinone derivative with significant biological activity. This compound is valued as a critical pharmaceutical intermediate and a key building block in advanced organic synthesis. It is primarily required by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel anthracycline and tetracycline-class antibiotic analogs.
• Anticancer Research: Used as a core scaffold in medicinal chemistry programs targeting DNA intercalation and topoisomerase inhibition for oncology drug discovery.
• Biochemical Research: Employed as a reference standard or active probe in biochemical assays to study enzyme interactions and cellular mechanisms.
• Organic Synthesis: Acts as a sophisticated chiral building block for constructing complex natural products and polycyclic molecules in academic and industrial R&D.
• API Development: Utilized in the research and development stages of new Active Pharmaceutical Ingredients (APIs) with targeted therapeutic effects.

Basic Information

Item	Details
Product Name	(7S)-7β-(3-Amino-2,3,6-Trideoxy-α-L-Lyxo-Hexopyranosyloxy)-9α-Methyl-7,8,9,10-Tetrahydro-6,9,11-Trihydroxynaphthacene-5,12-Dione
CAS No.	81844-87-3
Molecular Formula	C₂₅H₂₇NO₁₀
Molecular Weight	501.48 g/mol
Synonyms	9α-Methyl-7,8,9,10-tetrahydro-6,9,11-trihydroxy-7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]naphthacene-5,12-dione; 7-O-(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)-9α-methyl-7,8,9,10-tetrahydro-6,9,11-trihydroxynaphthacene-5,12-dione; 7S-(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyloxy)-9α-methyl-7,8,9,10-tetrahydro-6,9,11-trihydroxynaphthacene-5,12-dione; Aclarubicin derivative; Anthracycline intermediate; Naphthacenequinone glycoside
EINECS	Contact for details

Quality Control

Our (7S)-7β-(3-Amino-2,3,6-Trideoxy-α-L-Lyxo-Hexopyranosyloxy)-9α-Methyl-7,8,9,10-Tetrahydro-6,9,11-Trihydroxynaphthacene-5,12-Dione is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and opened under inert atmosphere conditions for prolonged handling to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to orange-red powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.