Description

Gnrh, Ac(4-Cl-Phe(1,2)-Trp(3)-Tyr(5)-Lys(6)-Ala(10))- CAS NO 81608-50-6 is a synthetic, modified decapeptide analog of Gonadotropin-Releasing Hormone (GnRH). This compound is engineered for enhanced stability and specific receptor binding affinity, making it a critical tool in advanced endocrinology research and pharmaceutical development. It is primarily utilized by research institutions, biotechnology companies, and pharmaceutical manufacturers focused on neuroendocrinology, reproductive biology, and peptide-based therapeutic discovery.

Application

• Biomedical Research: Fundamental studies on GnRH receptor signaling, hormone regulation, and neuroendocrine pathways.
• Pharmaceutical R&D: Serving as a reference standard or active pharmaceutical ingredient (API) in the development of novel therapeutics for reproductive disorders.
• In Vitro Diagnostics: Used in the development and calibration of immunoassays and receptor binding assays.
• Structure-Activity Relationship (SAR) Studies: Investigating the impact of specific amino acid modifications on peptide potency and selectivity.
• Veterinary Science: Research into reproductive management and fertility control in animals.

Basic Information

Product Name	Gnrh, Ac(4-Cl-Phe(1,2)-Trp(3)-Tyr(5)-Lys(6)-Ala(10))- CAS NO 81608-50-6
CAS No.	81608-50-6
Molecular Formula	C64H83ClN16O13
Molecular Weight	1295.9 g/mol (approx.)
Synonyms	Ac-[4-Cl-D-Phe1, D-Trp3, D-Tyr5, D-Lys6, D-Ala10]-GnRH; GnRH Antagonist Analog; [Ac-4-Cl-D-Phe1, D-Trp3, D-Tyr5, D-Lys6, D-Ala10]-LHRH; Modified GnRH Decapeptide; LHRH Antagonist (modified); Gonadorelin Antagonist Analog; [Ac-D-4-Cl-Phe1, D-Trp3, D-Tyr5, D-Lys6, D-Ala10]-GnRH
EINECS	Contact for details

Quality Control

Our Gnrh, Ac(4-Cl-Phe(1,2)-Trp(3)-Tyr(5)-Lys(6)-Ala(10))- CAS NO 81608-50-6 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.