Description

(-)-Cyanopindolol Hemifumarate is a high-purity, enantiomerically pure chemical compound used extensively in pharmacological and biochemical research. This compound serves as a potent and selective antagonist for β-adrenergic receptors, making it a critical tool for studying receptor function and signal transduction pathways. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies engaged in neuroscience, cardiovascular research, and drug discovery programs.

Application

• Pharmacological Research: As a selective β-adrenoceptor antagonist for in vitro and in vivo studies of receptor binding and function.
• Biochemical Assay Development: Used as a reference standard or active pharmaceutical ingredient (API) in the development of high-throughput screening assays.
• Neuroscience Studies: Investigation of the role of β-adrenergic receptors in neurological processes and disorders.
• Cardiovascular Research: Study of heart rate, blood pressure, and other cardiovascular parameters mediated by adrenergic signaling.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and validation in quality control laboratories.
• Academic & Institutional Research: Fundamental research in molecular pharmacology and cellular signaling pathways at universities and government institutes.

Basic Information

Product Name	(-)-Cyanopindolol Hemifumarate
CAS No.	81608-27-7
Molecular Formula	C₂₀H₂₂N₄O₂ • 0.5C₄H₄O₄
Molecular Weight	379.42 g/mol (free base: 326.42)
Synonyms	(-)-Cyanopindolol Hemifumarate; (S)-Cyanopindolol Hemifumarate; (S)-3-(2-Cyano-3-indolyloxy)-2-hydroxypropylaminoethoxy]indol Hemifumarate; Cyanopindolol Hemifumarate Salt; L-Cyanopindolol Hemifumarate; (S)-(−)-Cyanopindolol Hemifumarate; β-Adrenergic Blocker Cyanopindolol Hemifumarate; CAS 81608-27-7
EINECS	Contact for details

Quality Control

Our (-)-Cyanopindolol Hemifumarate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and enantiomeric excess. We support compliance with relevant research and development guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.