Description

N1-[5-[[3-[[Imino[(2-Phenylethyl)Amino]Methyl]Amino]Propyl]Amino]Pentyl]Bleomycinamide is a chemically modified derivative of the bleomycin family, a class of glycopeptide antibiotics known for their potent antitumor activity. This compound is of significant interest in pharmaceutical research and development, particularly for the synthesis of novel drug conjugates and targeted cancer therapies. It serves as a critical intermediate or active pharmaceutical ingredient (API) for researchers and manufacturers in the oncology and life sciences sectors seeking to develop next-generation chemotherapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel bleomycin-based anticancer drugs and antibody-drug conjugates (ADCs).
• Oncology Research: Used in biochemical and pharmacological studies to investigate mechanisms of action, DNA cleavage, and cytotoxicity against various cancer cell lines.
• Drug Discovery & Development: Serves as a precursor for creating modified bleomycin analogs with potentially improved efficacy, reduced toxicity, or altered pharmacokinetic profiles.
• Bioconjugation Studies: Utilized in research focused on linking cytotoxic agents to targeting molecules like antibodies, peptides, or ligands for targeted therapy.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	N1-[5-[[3-[[Imino[(2-Phenylethyl)Amino]Methyl]Amino]Propyl]Amino]Pentyl]Bleomycinamide
CAS No.	81481-57-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Bleomycinamide, N1-[5-[[3-[[Imino[(2-phenylethyl)amino]methyl]amino]propyl]amino]pentyl]-; Bleomycin A2 amide derivative; Phenylalanine-bleomycinamide; 81481-57-4; BLM derivative; Bleomycin analog; N1-Pentyl-N5-propyl bleomycinamide
EINECS	Contact for details

Quality Control

Our N1-[5-[[3-[[Imino[(2-Phenylethyl)Amino]Methyl]Amino]Propyl]Amino]Pentyl]Bleomycinamide is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. For long-term storage, consider desiccants and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.