Description

N1-[4-[[4-[[Imino[(2-Phenylethyl)Amino]Methyl]Amino]Butyl]Amino]Butyl]-7,8-Dihydrobleomycinamide is a chemically modified derivative of the bleomycin family, a class of glycopeptide antibiotics known for their potent antitumor activity. This compound is of significant interest in pharmaceutical research and development, particularly for the synthesis of novel chemotherapeutic agents and targeted drug delivery systems. It serves as a critical intermediate or active pharmaceutical ingredient (API) for researchers and manufacturers in the oncology and life sciences sectors.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of next-generation bleomycin analogs and chemotherapeutic agents.
• Oncology Research: Used in biochemical and pharmacological studies to investigate mechanisms of DNA cleavage and cytotoxicity.
• Antitumor Agent Development: Serves as a precursor in the development of novel, targeted cancer therapies with potentially improved efficacy and reduced side effects.
• Bioconjugation Studies: Utilized in research for attaching bleomycin derivatives to antibodies, peptides, or other targeting moieties for site-specific drug delivery.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in pharmaceutical manufacturing.
• Academic & Contract Research: Employed in university and CRO settings for fundamental research into antibiotic and anticancer compounds.

Basic Information

Product Name	N1-[4-[[4-[[Imino[(2-Phenylethyl)Amino]Methyl]Amino]Butyl]Amino]Butyl]-7,8-Dihydrobleomycinamide
CAS No.	81481-56-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	7,8-Dihydrobleomycinamide, N1-[4-[[4-[[Imino[(2-phenylethyl)amino]methyl]amino]butyl]amino]butyl]-; Bleomycin derivative; BLM derivative; N1-(4-((4-((Imino((2-phenylethyl)amino)methyl)amino)butyl)amino)butyl)-7,8-dihydrobleomycinamide; Modified bleomycin; Antitumor antibiotic intermediate.
EINECS	Contact for details

Quality Control

Our N1-[4-[[4-[[Imino[(2-Phenylethyl)Amino]Methyl]Amino]Butyl]Amino]Butyl]-7,8-Dihydrobleomycinamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and in original packaging until use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.