Description

(S)-(-)-Carteolol is the pharmacologically active enantiomer of carteolol, a non-selective β-adrenergic receptor antagonist. This high-purity chiral building block is critical for research and development in enantioselective synthesis and advanced pharmaceutical manufacturing. It is primarily utilized by pharmaceutical R&D teams, contract research organizations (CROs), and fine chemical producers focused on cardiovascular and ophthalmic drug development.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the research and production of enantiomerically pure β-blocker APIs.
• Biochemical Research: Used as a reference standard and active ligand in pharmacological studies of β-adrenergic receptors.
• Asymmetric Synthesis: Serves as a valuable starting material or model compound for developing new chiral synthesis and resolution methodologies.
• Analytical Standard: Employed for method development, calibration, and quality control in HPLC and chiral analysis within QC/QA laboratories.
• Metabolite Studies: Utilized in the synthesis and identification of drug metabolites for pharmacokinetic and toxicological profiling.

Basic Information

Product Name	(S)-(-)-Carteolol
CAS No.	81102-77-4
Molecular Formula	C16H24N2O3
Molecular Weight	292.38 g/mol
Synonyms	(S)-Carteolol; (-)-Carteolol; (S)-5-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]-3,4-dihydro-2(1H)-quinolinone; Levocarteolol; (S)-(-)-1-(tert-Butylamino)-3-[(5,6,7,8-tetrahydro-cis-6,7-dihydroxy-4-oxoquinolin-5-yl)oxy]-2-propanol; Carteolol S-(-) enantiomer
EINECS	Contact for details

Quality Control

Our (S)-(-)-Carteolol is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets stringent specifications for research and development use. A Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.