Description

Dexamethasone Palmitate is a lipophilic ester prodrug of the potent glucocorticoid dexamethasone. This chemical modification enhances its lipid solubility, which is a critical property for targeted drug delivery and formulation stability. It is primarily utilized in the pharmaceutical industry for the research and development of injectable depot formulations and advanced drug delivery systems. Professionals seeking Dexamethasone Palmitate CAS NO 80950-33-0 require a reliable supply of high-purity material to ensure consistent experimental and production outcomes.

Application

Dexamethasone Palmitate serves as a key intermediate and active pharmaceutical ingredient (API) in advanced therapeutic areas. Its primary applications include:

• Pharmaceutical R&D for long-acting, injectable steroid formulations.
• Development of liposomal and nanoparticle drug delivery systems to improve bioavailability and targeting.
• As a reference standard in analytical method development and quality control laboratories.
• Production of depot injections for sustained release in treating chronic inflammatory conditions.
• Research into prodrug strategies to modulate the pharmacokinetic profile of corticosteroids.
• Formulation of specialized topical or ophthalmic preparations requiring enhanced penetration.

Basic Information

Product Name	Dexamethasone Palmitate
CAS No.	80950-33-0
Molecular Formula	C37H59FO6
Molecular Weight	618.87 g/mol
Synonyms	Dexamethasone 21-Palmitate; 9-Fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-palmitate; 16α-Methyl-9α-fluoro-1,4-pregnadiene-11β,17α,21-triol-3,20-dione 21-palmitate; Dexamethasone Palmitate Ester; Dexapalmitate; Palmitic acid dexamethasone ester; (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione 21-hexadecanoate
EINECS	Contact for details

Quality Control

Our Dexamethasone Palmitate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for pharmaceutical research and development. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles as determined by HPLC, IR, and other relevant pharmacopeial methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.