Description

2-Amino-4-Fluorobenzonitrile is a versatile fluorinated aromatic nitrile and aniline derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both an amino and a fluorine substituent, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated heterocyclic compounds and active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing advanced fluorinated dyes and colorants with improved lightfastness and chromatic properties.
• Chemical Biology & Proteomics: Utilized as a scaffold or labeling reagent in the design of molecular probes and activity-based protein profiling (ABPP) agents.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Amino-4-Fluorobenzonitrile
CAS No.	80517-22-2
Molecular Formula	C7H5FN2
Molecular Weight	136.13 g/mol
Synonyms	4-Fluoro-2-aminobenzonitrile; 2-Amino-4-fluorobenzene carbonitrile; 4-Fluoroanthranilonitrile; 2-Cyano-5-fluoroaniline; 5-Fluoro-2-aminobenzonitrile; Benzonitrile, 2-amino-4-fluoro-; 2-Amino-4-fluorophenyl cyanide
EINECS	Contact for details

Quality Control

Our 2-Amino-4-Fluorobenzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the stringent requirements of our global clientele. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results for purity, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	95 - 100 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.