Description

Fluticasone Acetate is a synthetic corticosteroid ester with potent anti-inflammatory and immunosuppressive properties. This high-purity active pharmaceutical ingredient (API) is critical for the development and manufacture of advanced topical and inhalation therapies. It is primarily utilized by pharmaceutical companies and research institutions focused on dermatology and respiratory medicine to create effective treatments for chronic inflammatory conditions.

Application

• Pharmaceutical API: Primary active ingredient in topical creams and ointments for treating eczema, psoriasis, and dermatitis.
• Inhalation Formulations: Key component in dry powder inhalers (DPIs) and metered-dose inhalers (MDIs) for managing asthma and chronic obstructive pulmonary disease (COPD).
• Veterinary Medicine: Used in topical preparations for treating inflammatory skin conditions in animals.
• Research & Development: Serves as a reference standard and building block in pharmacological studies and the development of new corticosteroid derivatives.
• Cosmeceuticals: Incorporated into specialized formulations for addressing severe skin inflammation under medical supervision.

Basic Information

Product Name	Fluticasone Acetate
CAS No.	80474-24-4
Molecular Formula	C26H31F3O6S
Molecular Weight	528.59 g/mol
Synonyms	S-Fluticasone Acetate; Fluticasone 17-Acetate; (6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic Acid S-Fluoromethyl Ester; 17-Acetoxy-6α,9-difluoro-11β-hydroxy-16α-methyl-3-oxoandrosta-1,4-diene-17β-carbothioic Acid S-(Fluoromethyl) Ester; Fluticasone Propionate EP Impurity C; Fluticasone Propionate Related Compound C; CC-01; SQ-41225
EINECS	Contact for details

Quality Control

Our Fluticasone Acetate is manufactured under strict quality management systems. Each batch is tested to ensure compliance with relevant pharmacopeial standards such as USP and EP, with specifications covering identity, purity, assay, and related substances. A comprehensive Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and consistent quality for your formulation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.