Description

Fluticasone Propionate is a synthetic corticosteroid of the glucocorticoid class, widely recognized for its potent anti-inflammatory and immunosuppressive properties. Its primary commercial value lies in its critical role as the active pharmaceutical ingredient (API) in a range of topical and inhaled medications for treating inflammatory conditions. This high-purity compound is essential for manufacturers in the global pharmaceutical industry, particularly those developing and producing treatments for asthma, allergic rhinitis, and various dermatological disorders such as eczema and psoriasis.

Application

• Active Pharmaceutical Ingredient (API) in metered-dose and dry powder inhalers for asthma and COPD management.
• Key component in nasal sprays for the treatment of allergic and non-allergic rhinitis.
• Primary agent in topical creams, ointments, and lotions for dermatological conditions like eczema, psoriasis, and contact dermatitis.
• Used in veterinary pharmaceutical formulations for anti-inflammatory applications.
• Reference standard in analytical laboratories for quality control and research purposes.
• Intermediate in the synthesis of more complex corticosteroid derivatives for specialized drug development.

Basic Information

Product Name	Fluticasone Propionate
CAS No.	80474-14-2
Molecular Formula	C25H31F3O5S
Molecular Weight	500.57 g/mol
Synonyms	Fluticasone 17-propionate; S 9260; CC-01; Flixonase; Flixotide; Cutivate; Flutivate; (6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic acid S-fluoromethyl ester
EINECS	Contact for details

Quality Control

Our Fluticasone Propionate is manufactured under strict quality management systems, targeting compliance with major pharmacopoeial standards such as USP and EP. Every batch undergoes comprehensive analytical testing, including identification, assay, impurity profiling, and residual solvent analysis. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to ensure full traceability and quality assurance for our B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	NMT 1.0%
Related Substances (HPLC)	Total impurities: NMT 2.0% Any individual impurity: NMT 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	NMT 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.