Description

(2-Fluoro-Phenyl)-Oxo-Acetonitrile is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. Its core value lies in the reactive nitrile and ketone functional groups adjacent to a fluorinated benzene ring, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require high-purity intermediates for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for transition metal catalysis and asymmetric synthesis.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of specialty polymers and advanced organic electronic materials.
• Fluorine Chemistry Studies: A valuable substrate for investigating new fluorination reactions and studying the electronic effects of the fluorine substituent.

Basic Information

Product Name	(2-Fluoro-Phenyl)-Oxo-Acetonitrile
CAS No.	80277-41-4
Molecular Formula	C9H6FNO
Molecular Weight	163.15 g/mol
Synonyms	2-Fluorobenzoyl cyanide; 2-Fluorophenylglyoxylonitrile; (2-Fluorobenzoyl)formonitrile; α-Oxo-2-fluorobenzeneacetonitrile; 2-Fluorophenyl(oxo)acetonitrile; Glyoxylonitrile, 2-fluorophenyl-; 2-Fluorobenzoyl cyanide; 2-Fluorophenylglyoxal cyanohydrin (tautomer)
EINECS	Contact for details

Quality Control

Our (2-Fluoro-Phenyl)-Oxo-Acetonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.