Description

Butanoic Acid, 2-Fluoro-3-Oxo-, Methyl Ester (9Ci) is a specialized fluorinated ketoester building block, offering a unique combination of a reactive β-ketoester moiety and a fluorine atom for advanced molecular synthesis. This compound matters for its role in facilitating complex organic transformations, particularly in the development of novel fluorinated pharmaceuticals and agrochemicals where fluorine introduction is critical for modulating biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate fluorine into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated active pharmaceutical ingredients (APIs), especially those containing β-ketoester or heterocyclic frameworks.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides where the fluorine atom enhances lipophilicity and target binding.
• Fluorine Chemistry: Serves as a versatile building block in academic and industrial research for exploring new fluorination reactions and creating fluorinated compound libraries.
• Material Science Precursor: Potential use in the synthesis of fluorinated monomers or additives for specialty polymers with altered surface properties or stability.
• Chemical Synthesis: Employed in Claisen condensations, Michael additions, and other carbon-carbon bond-forming reactions to construct complex, fluorinated molecules.

Basic Information

Item	Details
Product Name	Butanoic Acid, 2-Fluoro-3-Oxo-, Methyl Ester (9Ci)
CAS No.	80171-29-5
Molecular Formula	C5H7FO3
Molecular Weight	134.10 g/mol
Synonyms	Methyl 2-Fluoro-3-oxobutanoate; 2-Fluoro-3-oxobutanoic Acid Methyl Ester; Methyl 2-Fluoroacetoacetate; 3-Oxo-2-fluorobutanoic Acid Methyl Ester; Fluoromethyl Acetoacetate; 80171-29-5; Butanoic acid, 2-fluoro-3-oxo-, methyl ester
EINECS	Contact for details

Quality Control

Our Butanoic Acid, 2-Fluoro-3-Oxo-, Methyl Ester (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided and available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.