Description

1,2-Dihydro-Betamethasone 17,21-Dipropionate is a synthetic corticosteroid derivative, specifically a dihydro and dipropionate ester form of betamethasone. This compound is valued for its potent anti-inflammatory and immunosuppressive properties, offering enhanced stability and bioavailability for advanced pharmaceutical formulations. It is primarily required by pharmaceutical R&D laboratories and manufacturers developing topical corticosteroids, dermatological creams, and other specialized therapeutic products.

Application

• Active Pharmaceutical Ingredient (API) in topical corticosteroid formulations for treating skin conditions like eczema, psoriasis, and dermatitis.
• Key Intermediate in the synthesis of more complex steroid-based pharmaceutical compounds.
• Research Chemical for pharmacological studies investigating glucocorticoid receptor activity and anti-inflammatory mechanisms.
• Dermatological Product Development for creams, ointments, and lotions requiring a potent, stabilized corticosteroid.
• Veterinary Medicine for developing anti-inflammatory treatments for animals.

Basic Information

Product Name	1,2-Dihydro-Betamethasone 17,21-Dipropionate
CAS No.	80163-83-3
Molecular Formula	C28H37FO7
Molecular Weight	504.59 g/mol
Synonyms	Betamethasone 17,21-Dipropionate Dihydro Derivative; 9α-Fluoro-11β,17α,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate; 1,2-Dihydrobetamethasone dipropionate; Dihydrobetamethasone dipropionate; (11β,16β)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate
EINECS	Contact for details

Quality Control

Our 1,2-Dihydro-Betamethasone 17,21-Dipropionate is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade standards suitable for pharmaceutical research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.