Description

7-Chloro Epinastine Hydrochloride is a key pharmaceutical intermediate and a chlorinated derivative of the antihistamine epinastine. This compound is critical for research and development in the synthesis of novel active pharmaceutical ingredients (APIs) targeting histamine H1 receptors. It is primarily utilized by pharmaceutical manufacturers, R&D laboratories, and fine chemical synthesis specialists working on advanced therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of advanced antihistamine and anti-allergy drug candidates.
• Active Pharmaceutical Ingredient (API) Research: Serves as a precursor or a modified lead compound in the development of new therapeutic entities.
• Biochemical Research: Used in pharmacological studies to investigate histamine receptor binding and antagonism mechanisms.
• Fine Chemical Synthesis: Employed in custom synthesis and process development for high-value, complex organic molecules.
• Reference Standard: Can be utilized as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	7-Chloro Epinastine Hydrochloride
CAS No.	80012-45-9
Molecular Formula	C16H15ClN4•HCl
Molecular Weight	343.23 g/mol
Synonyms	7-Chloro-3-amino-9,13b-dihydro-1H-dibenz[c,f]imidazo[1,5-a]azepine Hydrochloride; 7-Chloroepinastine HCl; 7-Cl-Epinastine Hydrochloride; Epinastine 7-Chloro Derivative Hydrochloride; (3-Amino-7-chloro-9,13b-dihydro-1H-dibenz[c,f]imidazo[1,5-a]azepin-2-yl)amine Hydrochloride
EINECS	Contact for details

Quality Control

Our 7-Chloro Epinastine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets stringent specifications for pharmaceutical R&D use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.