Description

Pentafluoronitrobenzene CAS NO 880-78-4 is a highly fluorinated aromatic compound characterized by a nitro group and five fluorine atoms on the benzene ring. This unique structure makes it a versatile and valuable building block in advanced organic synthesis, particularly for introducing fluorinated aromatic systems. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, including kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Building block for developing advanced herbicides, pesticides, and fungicides with enhanced properties.
• Liquid Crystal & OLED Material: Used in the production of fluorinated components for electronic display and lighting technologies.
• Polymer Modification: Serves as a monomer or modifier to create specialty polymers with improved chemical resistance and stability.
• Dye & Pigment Manufacturing: Intermediate for synthesizing fluorinated dyes and pigments with unique color fastness.
• Cross-coupling Reactions: An excellent substrate for nucleophilic aromatic substitution (SNAr) and palladium-catalyzed coupling reactions to form complex biaryl structures.

Basic Information

Item	Details
Product Name	Pentafluoronitrobenzene
CAS No.	880-78-4
Molecular Formula	C6F5NO2
Molecular Weight	213.07 g/mol
Synonyms	1,2,3,4,5-Pentafluoronitrobenzene; Pentafluoronitrobenzene; Nitropentafluorobenzene; Perfluoronitrobenzene; PNFB; 2,3,4,5,6-Pentafluoronitrobenzene; NSC 9235; Nitroperfluorobenzene
EINECS	212-921-7

Quality Control

Our Pentafluoronitrobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and GC-MS for identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	28 - 32 °C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.