Description

2-Methoxy-N,N,β-Trimethyl-10H-Phenothiazine-10-Propylamine is a high-purity, functionalized phenothiazine derivative with the CAS number 851-68-3. This compound serves as a critical advanced intermediate in the synthesis of complex pharmaceutical actives and specialty organic materials. It is primarily required by research and development laboratories, fine chemical manufacturers, and pharmaceutical companies engaged in the development of novel therapeutic agents and high-performance chemical products.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of tricyclic antidepressant and antipsychotic drug candidates.
• Organic Synthesis Reagent: Used in research for constructing complex nitrogen and sulfur-containing heterocycles.
• Material Science Research: Investigated as a precursor for functional dyes, charge-transfer complexes, and electroactive polymers.
• Biochemical Research: Potential use in developing fluorescent probes or ligands for receptor binding studies due to the phenothiazine core.
• Catalyst Ligand Precursor: Can be modified to create novel ligands for transition metal catalysis.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	2-Methoxy-N,N,β-Trimethyl-10H-Phenothiazine-10-Propylamine
CAS No.	851-68-3
Molecular Formula	C19H24N2OS
Molecular Weight	328.47 g/mol
Synonyms	10-[3-(Dimethylamino)propyl]-2-methoxy-10H-phenothiazine; 2-Methoxy-10-(3-dimethylaminopropyl)phenothiazine; Methoxypromazine; 851-68-3; 10H-Phenothiazine-10-propanamine, 2-methoxy-N,N,β-trimethyl-; 2-Methoxy-N,N,β-trimethyl-10H-phenothiazine-10-propanamine; Methopromazine (base)
EINECS	Contact for details

Quality Control

Our 2-Methoxy-N,N,β-Trimethyl-10H-Phenothiazine-10-Propylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are supplied with every shipment to ensure compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, handling should be performed under subdued lighting where practical.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.