Description

Formestane is a selective, steroidal aromatase inhibitor used in pharmaceutical research and development. This compound is crucial for its role in modulating estrogen synthesis, making it a valuable tool for studying endocrine-related pathways. It is primarily utilized by pharmaceutical companies, research institutions, and contract development and manufacturing organizations (CDMOs) focused on oncology, endocrinology, and steroid biochemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of advanced steroid-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and investigational tool in studies of aromatase enzyme activity and inhibition.
• Oncology Research: Employed in preclinical research for hormone-dependent cancers, such as certain breast cancers, to understand estrogen modulation.
• Academic Studies: Serves as a critical reagent in university and institutional labs for endocrinology and steroid metabolism research.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing of related substances.

Basic Information

Product Name	Formestane
CAS No.	848-35-1
Molecular Formula	C19H26O3
Molecular Weight	302.41 g/mol
Synonyms	4-Hydroxyandrost-4-ene-3,17-dione; 4-Hydroxyandrostenedione; 4-OHA; Lentaron (brand name); CGP 32349; Formestanum; Androst-4-ene-3,17-dione, 4-hydroxy-
EINECS	Contact for details

Quality Control

Our Formestane is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications. We support development and commercial projects requiring material that meets high-purity standards for research and pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Unknown Impurity	≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.