Description

Benzene, 2-Nitro-1-Propoxy-4-(Trifluoromethyl)- is a specialized nitroaromatic compound featuring a trifluoromethyl group and a propoxy substituent, making it a valuable building block in advanced organic synthesis. This compound matters for its unique molecular architecture, which imparts specific electronic and steric properties crucial for developing high-performance materials and active pharmaceutical ingredients. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted functionalities.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly those requiring fluorinated or nitro-substituted aromatic cores.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Acts as a precursor in the synthesis of fluorinated organic compounds for electronic applications, including liquid crystal displays and organic light-emitting diodes.
• Polymer Modification: Employed to introduce specific functional groups into polymer chains, altering physical properties like solubility, thermal stability, or refractive index.
• Dye & Pigment Manufacturing: Utilized as an intermediate for creating complex, color-fast nitroaromatic dyes and pigments.
• Cross-Coupling Reactions: Functions as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to construct more complex biaryl structures.

Basic Information

Product Name	Benzene, 2-Nitro-1-Propoxy-4-(Trifluoromethyl)-
CAS No.	837-99-0
Molecular Formula	C10H10F3NO3
Molecular Weight	249.19 g/mol
Synonyms	1-Propoxy-2-nitro-4-(trifluoromethyl)benzene; 2-Nitro-1-propoxy-4-(trifluoromethyl)benzene; 4-(Trifluoromethyl)-2-nitro-1-propoxybenzene; α,α,α-Trifluoro-2-nitro-p-propoxy toluene; 2-Nitro-4-(trifluoromethyl)phenyl propyl ether; 1-Nitro-2-propoxy-5-(trifluoromethyl)benzene; p-Propoxy-α,α,α-trifluoro-o-nitrotoluene
EINECS	Contact for details

Quality Control

Our Benzene, 2-Nitro-1-Propoxy-4-(Trifluoromethyl)- is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most sensitive synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.