Description

Diethyl 2,3-Difluoromaleate is a high-purity fluorinated organic building block, specifically a diester derivative of difluoromaleic acid. This compound is valued for its unique reactivity as a versatile synthon in advanced organic synthesis, enabling the efficient introduction of fluorinated maleate motifs into complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries for constructing novel active ingredients and functional monomers.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing fluorinated active pharmaceutical ingredients (APIs) and prodrugs, leveraging fluorine's ability to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of novel fluorinated herbicides, fungicides, and plant growth regulators.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for creating specialty polymers with enhanced chemical resistance, surface properties, or optical characteristics.
• Organic Synthesis Reagent: Acts as a dienophile in Diels-Alder reactions or an electrophile in Michael additions for constructing complex, fluorinated heterocycles and alicyclic compounds.
• Liquid Crystal & Electronic Chemical Precursor: Employed in the development of fluorinated components for liquid crystal displays (LCDs) and organic electronic materials.

Basic Information

Product Name	Diethyl 2,3-Difluoromaleate
CAS No.	815-97-4
Molecular Formula	C8H10F2O4
Molecular Weight	208.16 g/mol
Synonyms	Diethyl (Z)-2,3-Difluoromaleate; 2,3-Difluoromaleic Acid Diethyl Ester; Diethyl (Z)-2,3-Difluorobut-2-enedioate; Ethyl 2,3-Difluoromaleate; 2,3-Difluoromaleic Acid Diethyl Ester; But-2-enedioic acid, 2,3-difluoro-, diethyl ester, (Z)-
EINECS	Contact for details

Quality Control

Our Diethyl 2,3-Difluoromaleate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and structural confirmation, to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) providing batch-specific data is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.