Description

Porfiromycin is a potent antibiotic and antitumor agent belonging to the mitomycin family. This compound is valued for its bioreductive alkylating properties, which enable it to target and damage the DNA of hypoxic cells, a key characteristic of many solid tumors. It is primarily utilized in advanced research and development within the pharmaceutical and biotechnology sectors. Researchers and manufacturers seeking a high-purity, reliable supply for oncology studies and novel therapeutic development will find this product essential.

Application

• Oncology Research: As a DNA alkylating agent for studying mechanisms of action against hypoxic tumor cells.
• Antibiotic Development: Serves as a reference standard and active pharmaceutical ingredient (API) in the development of novel antimicrobial agents.
• Biochemical Studies: Used to investigate bioreductive activation pathways and DNA cross-linking in cellular models.
• Pharmaceutical Intermediates: Acts as a key synthetic intermediate for the preparation of more complex mitomycin analogs.
• Preclinical Studies: Employed in in vitro and in vivo models to evaluate efficacy and toxicity profiles.

Basic Information

Product Name	Porfiromycin
CAS No.	801-52-5
Molecular Formula	C16H20N4O5
Molecular Weight	348.36 g/mol
Synonyms	Porfiromycin; 7-(Aminocarbonyloxy)mitomycin; U-14,743; NSC-56410; Antibiotic U-14743; Mitomycin C derivative; 7-Carbamoyloxymitomycin C; 7β-(Carbamoyloxy)mitomycin C
EINECS	Contact for details

Quality Control

Our Porfiromycin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed batch-specific data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, consider storage at 2-8°C.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.