Description

Trimeprazine is a phenothiazine derivative with significant pharmacological activity, primarily known for its potent antihistaminic and sedative properties. This compound is a critical intermediate in the synthesis of advanced pharmaceutical agents, offering reliable performance in complex chemical processes. It is essential for research institutions and pharmaceutical manufacturers developing treatments for allergic conditions, pruritus, and as a pre-anesthetic medication.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of trimeprazine tartrate and other derivative drugs.
• Antihistamine Research: Used in R&D for developing and testing new H1-receptor antagonist formulations.
• Sedative & Antipruritic Agent: Serves as a reference standard and active component in studies for sedative and anti-itch medications.
• Veterinary Medicine: Employed in formulations to manage allergic dermatitis and provide sedation in animals.
• Chemical Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing.
• Academic & Clinical Research: Fundamental compound for pharmacological studies exploring phenothiazine effects on the central nervous system.

Basic Information

Product Name	Trimeprazine
CAS No.	84-96-8
Molecular Formula	C18H22N2S
Molecular Weight	298.45 g/mol
Synonyms	Alimemazine; Temaril; Panectyl; Repeltin; Variargil; 10-(3-Dimethylamino-2-methylpropyl)phenothiazine; 10H-Phenothiazine-10-propanamine, N,N,β-trimethyl-
EINECS	201-581-8

Quality Control

Our Trimeprazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by HPLC, IR, and other pharmacopeial methods. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, and we support our clients' regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.