Description

Chlorcyclizine is a piperazine-class antihistamine compound with the CAS registry number 82-93-9. It is a versatile active pharmaceutical ingredient (API) valued for its potent H1-receptor antagonism, which forms the basis for its therapeutic effects. This compound is primarily required by pharmaceutical manufacturers for the development and production of antihistamine and antiemetic medications.

Application

• Pharmaceutical API: Core active ingredient in prescription and over-the-counter antihistamine formulations.
• Antiallergic Medications: Used to treat symptoms of allergies, such as hay fever, urticaria (hives), and allergic rhinitis.
• Antiemetic Agent: Employed in formulations to prevent and treat nausea and vomiting, including motion sickness.
• Pruritus Relief: A component in topical or systemic treatments for relieving itching associated with various dermatological conditions.
• Veterinary Pharmaceuticals: Used in animal health products for managing allergic reactions and motion sickness in pets and livestock.
• Research & Development: Serves as a reference standard and a key intermediate in pharmacological research for developing new therapeutic agents.

Basic Information

Product Name	Chlorcyclizine
CAS No.	82-93-9
Molecular Formula	C18H21ClN2
Molecular Weight	300.83 g/mol
Synonyms	1-(4-Chlorobenzhydryl)-4-methylpiperazine; Chlorcyclizine Hydrochloride (salt form); Histachlorazine; Diparalene; Perazil; Antamin; Prulet; Trihistan; Chlorcyclizine Dihydrochloride
EINECS	201-447-7

Quality Control

Our Chlorcyclizine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.