Description

Cyclizine is a piperazine derivative with significant pharmacological activity, widely recognized for its antiemetic and antihistaminic properties. This compound is crucial for ensuring product quality and consistency in the development and manufacturing of pharmaceutical formulations. It is primarily required by pharmaceutical companies and research institutions engaged in the production of medications for motion sickness, nausea, and vertigo, as well as in neurological research applications.

Application

• Pharmaceutical Active Ingredient (API): Primary use as the active component in antiemetic and antihistamine medications.
• Motion Sickness Prevention: Formulation into tablets, capsules, or injectables for the prevention and treatment of nausea and vomiting associated with motion.
• Vertigo Management: Used in therapeutic agents aimed at managing symptoms of vestibular disorders and vertigo.
• Research & Development: Serves as a key reference standard and intermediate in pharmacological and toxicological studies.
• Veterinary Pharmaceuticals: Application in veterinary medicine for the control of nausea in animals.

Basic Information

Product Name	Cyclizine
CAS No.	82-92-8
Molecular Formula	C18H22N2
Molecular Weight	266.38 g/mol
Synonyms	1-Diphenylmethyl-4-methylpiperazine; 1-(Diphenylmethyl)-4-methylpiperazine; Marzine; N-Benzhydryl-N'-methylpiperazine; N-Methyl-4-(diphenylmethyl)piperazine; Valoid
EINECS	201-447-7

Quality Control

Our Cyclizine is manufactured under strict quality systems to ensure it meets the high-purity standards required for pharmaceutical applications. Each batch is tested against rigorous specifications, including identity, purity, and impurity profiles. Certificates of Analysis (COA) documenting compliance with relevant pharmacopeial standards (such as USP/EP) are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.